RAS GTPase inhibitor 1 TFA

SKU: orb1708697

Description

RAS GTPase inhibitor 1 is a small molecule that targets RAS GTPase activity, demonstrating potential antitumor effects. It is used in vitro for studying RAS signaling in cancer cells and in vivo for preclinical evaluation of tumor growth inhibition in models of RAS-driven cancers like pancreatic and colorectal malignancies.

Research Area

Pharmacology & Drug Discovery, Signal Transduction, Stem Cell & Developmental Biology; Pharmacology & Drug Discovery

Key Properties

• CAS Number: 2252242-32-1
• MW: 565.99
• Purity: 99.66% (May vary between batches)
• Formula: C₂₇H₂₈ClF₄N₅O₂
• SMILES: C(C(O)=O)(F)(F)F.N([C@H](CC)C1CC1)C=2C3=C(C(=CC=C3)C=4CCNCC4)N=C(NC5=CC(Cl)=C(F)C=C5)N2
• Target: Ras,Raf

Bioactivity

• Target IC50:
  H727 cells:< 1 μM |H727 cells:< 1 μM

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

H727 cells, RAS GTPase inhibitor 1, RasGAP

Compound Identifiers

PubChem CID

146014439