Rapastinel

SKU: orb1695663

Description

Rapastinel (TPPT-amide, GLYX-13) is a functional N-methyl-D-aspartate receptor (NMDAR) modulator. It has been widely used in preclinical research to investigate mechanisms of synaptic plasticity, cognition, and rapid-acting antidepressant effects in both in vitro and in vivo experimental models.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 117928-94-6
• MW: 413.47
• Purity: 99.67% (May vary between batches)
• Formula: C₁₈H₃₁N₅O₆
• SMILES: C[C@@H](O)[C@H](N)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H]([C@@H](C)O)C(N)=O
• Target: NMDAR,iGluR
• Solubility: DMSO:32 mg/mL (77.39 mM)

Storage & Handling

• Storage: keep away from direct sunlight,store under nitrogen,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

NMDA receptor, inhibit, Ionotropic glutamate receptors, GLYX 13, GLYX13, GLYX-13, iGluR, Inhibitor, Rapastinel, Thr-Pro-Pro-Thr-NH2, TPPT-amide

Compound Identifiers

PubChem CID

14539800