Rapalink-1

SKU: orb1679099

Description

Rapalink-1 is a brain-penetrant mTOR inhibitor that protects endothelial cells from ethanol-induced oxidative stress, DNA damage, and senescence. It effectively inhibits the mTORC1-4E-BP1 pathway in vivo and demonstrates anticancer activity, making it a valuable compound for research in areas such as prostate cancer, aging, and neurobiology.

Research Area

Cell Biology, Signal Transduction

Key Properties

• CAS Number: 1887095-82-0
• MW: 1784.14
• Formula: C₉₁H₁₃₈N₁₂O₂₄
• SMILES: NC1=C2C(=NN(CCCCNC(CCOCCOCCOCCOCCOCCOCCOCCOCCN3C=C(COCCO[C@H]4[C@H](OC)C[C@H](C[C@@H](C)[C@]5(OC(=O)[C@]6(N(C(=O)C(=O)[C@]7(O)O[C@@](CC[C@H]7C)(C[C@H](OC)\C(\C)=C\C=C\C=C/[C@@H](C)C[C@@H](C)C(=O)[C@H](OC)[C@H](O)/C(/C)=C\[C@@H](C)C(=O)C5)[H])CCCC6)[H])[H])CC4)N=N3)=O)C2=NC=N1)C=8C=C9C(=CC8)OC(N)=N9
• Target: Autophagy,mTOR

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

175647741