Ramoplanin

SKU: orb1983787

Description

Ramoplanin is a lipoglycopeptide antibiotic isolated from Actinoplanes species. It acts by binding to lipid II, thereby inhibiting peptidoglycan biosynthesis in Gram-positive bacteria. This mechanism supports its research applications in studying antibiotic resistance and bacterial cell wall assembly in both in vitro and in vivo models.

Research Area

Infectious Disease & Virology

Key Properties

• CAS Number: 76168-82-6
• Target: Antibacterial,Antibiotic
• Solubility: DMSO:30 mg/mL

Bioactivity

• In Vivo:
  A mouse model treated with Ramoplanin (100 μg/mL) in drinking water for 8 days was found to effectively inhibit the ability of Vancomycin-resistant Enterococcus (VRE) to colonize the intestines of mice.
• In Vitro:
  Ramoplanin is a glycoliptide antibiotic with activity against gram-positive bacteria. The MIC of Ramoplanin against susceptible gram-positive cocci was < = 2.0 μg/mL.

Storage & Handling

• Storage: keep away from moisture,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Ramoplanin, Bacteria

Quick Database Links

Gene Symbol

Antibacterial,Antibiotic