RAF-IN-4

SKU: orb3174784

Description

RAF-IN-4 (Compound 120) is an inhibitor of Raf kinase. It has IC50 values of 134.3 nM for B-Raf, 118.6 nM for B-Raf(V600E), and 276.7 nM for C-Raf. This compound inhibits cancer cell proliferation by blocking the Raf signaling pathway. RAF-IN-4 is applicable in cancer research, including studies on lung and breast cancer.

Research Area

Signal Transduction

Key Properties

• CAS Number: 1445582-05-7
• MW: 414.48
• Formula: C₂₃H₁₈N₄O₂S
• SMILES: O=S(=O)(C=1C=CC(=CC1)C2=CC=C3N=CC=C(NC=4C=CC=C5NN=CC54)C3=C2)C
• Target: Raf

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Raf