Raclopride

SKU: orb1299640

Description

Raclopride is a selective dopamine D2/D3 receptor antagonist. It is widely used in neuroscience research to study receptor function, dopaminergic pathways, and behaviors in both in vitro binding assays and in vivo animal models of psychiatric and neurological disorders.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 84225-95-6
• MW: 347.24
• Purity: 99.17% (May vary between batches)
• Formula: C₁₅H₂₀Cl₂N₂O₃
• SMILES: CCN1CCC[C@H]1CNC(=O)c1c(O)c(Cl)cc(Cl)c1OC
• Target: Dopamine Receptor
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (11.52 mM);DMSO:100 mg/mL (287.99 mM)

Bioactivity

• Target IC50:
  D4:2,400nM|D1:18,000 nM|D3:3.5nM|D2:1.8nM
• In Vivo:
  Raclopride passes the blood brain barrier and can be used in in vivo binding and autoradiography studies of the dopamine system under normal and pathological conditions such as Huntington's disease

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

inhibit, Inhibitor, dopaminergic D2 receptor, DopamineReceptor, Dopamine, Dopamine Receptor, central, benzamide, antiaggressive, Raclopride

Compound Identifiers

PubChem CID

3033769