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Rac1-IN-5

SKU: orb3136602

Description

Rac1-IN-5 is a selective, reversible inhibitor of the RAC1 protein with a dissociation constant (KD) of 30 nM. It competes specifically with guanine nucleotides for binding to RAC proteins, effectively blocking RAC1 activity and RAC1-dependent cellular functions. In vivo, Rac1-IN-5 exhibits anti-tumor metastasis effects and can improve survival rates. This compound is applicable for research on aggressive cancers such as triple-negative breast cancer and colon cancer.

Research Area

Metabolism Research, Neuroscience, Signal Transduction

Images & Validation

Key Properties

CAS Number694515-65-6
MW486.60
FormulaC24H26N2O5S2
SMILESO=C(NC1=CC=C(C=C1)S(=O)(=O)NC2=CC(OC)=CC=C2OC)CCSC3=CC=C(C=C3)C
TargetAkt,Acyltransferase,Ras

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information