(Rac)-Roscovitine

SKU: orb3028560

Description

(Rac)-Roscovitine ((Rac)-Seliciclib) is a selective inhibitor of cyclin-dependent kinases (CDKs). It competes with ATP for binding at the active site of CDKs, thereby inhibiting their phosphorylation activity. This compound induces apoptosis in cancer cells and holds potential for the study of conditions like cancer, neurodegenerative diseases, heart diseases, viral and protozoal infections, glomerulonephritis, and chronic inflammation, all of which are associated with CDK dysregulation.

Research Area

Cell Biology

Key Properties

• CAS Number: 186692-44-4
• MW: 354.449
• Formula: C₁₉H₂₆N₆O
• SMILES: OCC(NC=1N=C(NCC=2C=CC=CC2)C=3N=CN(C3N1)C(C)C)CC
• Target: Apoptosis,CDK

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Apoptosis,CDK