(Rac)-Lonafarnib

SKU: orb1744722

Description

Lonafarnib (Sch66336 racemate) is a potent, orally bioavailable farnesyltransferase inhibitor with low nM IC50 values against H-, K-, and N-ras isoforms. It is also active against hepatitis delta virus (HDV) and has been utilized in both in vitro and in vivo cancer and virology research models.

Research Area

Metabolism Research, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 193275-86-4
• MW: 638.82
• Formula: C₂₇H₃₁Br₂ClN₄O₂
• SMILES: BrC1=C2C(C=3C(CCC2=CC(Cl)=C1)=CC(Br)=CN3)C4CCN(C(CC5CCN(C(N)=O)CC5)=O)CC4
• Target: Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

9852353