(Rac)-Ketoconazole

SKU: orb3134478

Description

(Rac)-Ketoconazole ((Rac)-R 41400) is an orally active antifungal imidazole compound. It inhibits ergosterol synthesis in fungi by targeting the cytochrome P450-dependent enzyme, 14α-sterol demethylase (CYP51), on the fungal cell membrane. This disruption leads to dysfunction of the cell membrane, ultimately hindering fungal growth and proliferation. (Rac)-Ketoconazole is applicable in studying fungal infections.

Research Area

Infectious Disease & Virology, Metabolism Research, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 79156-75-5
• MW: 531.43
• Formula: C₂₆H₂₈Cl₂N₄O₄
• SMILES: O=C(N1CCN(C2=CC=C(OCC3OC(OC3)(C4=CC=C(Cl)C=C4Cl)CN5C=NC=C5)C=C2)CC1)C
• Target: Cytochromes P450,Antifungal

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Cytochromes P450,Antifungal