(Rac)-Idroxioleic acid

SKU: orb1308041

Description

(Rac)-2-Hydroxyoleic acid is a fatty acid amide hydrolase (FAAH) inhibitor that exerts anti-tumor activity by targeting and modifying plasma membrane lipid structure. It has been investigated in vitro and in vivo for its potential in oncology research, particularly in studies of membrane lipid therapy and cancer cell proliferation.

Research Area

Cell Biology, Signal Transduction

Key Properties

• CAS Number: 56472-29-8
• MW: 298.46
• Purity: 99.74% (May vary between batches)
• Formula: C₁₈H₃₄O₃
• SMILES: C(CCC(C(O)=O)O)CCC/C=C\CCCCCCCC
• Target: Apoptosis
• Solubility: DMSO:50 mg/mL (167.53 mM)

Bioactivity

• Target IC50:
  Jurkat cells:40 μM
• In Vivo:
  In nude mice infected with Jurkat cells, Minerval significantly inhibits tumour growth.
• In Vitro:
  Minerval (25-50 μM; 72 hours) causes a marked and concentration-dependent increase in the proteolytic cleavage of PARP, a molecular marker of apoptosis. Minerval (25-75 μM; 72 hours) impairs Jurkat cell growth in a time- and concentration-dependent manner (IC50: 40 μM).
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Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

acid, (Rac)Idroxioleic acid, (Rac)-Idroxioleic acid, (Rac) Idroxioleic acid, 2-Hydroxyoleic acid, 2-OHOA, Apoptosis, Inhibitor, Idroxioleic acid, membrane, inhibit, oleic, Minerval, plasma

Compound Identifiers

PubChem CID

9796304