(Rac)-BL-918

SKU: orb1708718

Description

(Rac)-BL-918 is the racemic mixture of BL-918, a potent ULK1 activator with an EC₅₀ of 24.14 nM. It induces protective autophagy in cellular models and has shown potential for Parkinson's disease research in preclinical studies, highlighting its utility for investigating autophagy-related pathways in vitro and in vivo.

Research Area

Signal Transduction

Key Properties

• CAS Number: 2435589-07-2
• MW: 533.44
• Purity: 97.03% (May vary between batches)
• Formula: C₂₃H₁₅F₈N₃OS
• SMILES: O=C(NC1=CC=C(F)C=C1F)C(NC(=S)NC=2C=C(C=C(C2)C(F)(F)F)C(F)(F)F)C=3C=CC=CC3
• Target: Others,Autophagy
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (7.5 mM);DMSO:≥ 100 mg/mL

Storage & Handling

• Storage: store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

(Rac)BL918, (Rac)-BL918, (Rac) BL 918, BL918, BL-918, BL 918

Compound Identifiers

PubChem CID

138377593