(Rac)-BIO8898

SKU: orb1983396

Description

(Rac)-BIO8898 is a small molecule inhibitor that disrupts the CD40-CD154 co-stimulatory pathway by blocking CD154 binding to CD40, exhibiting an IC50 of 25 μM. This compound is utilized in immunological research to study T-cell mediated responses and has been applied in both in vitro assays and in vivo models of inflammation and autoimmunity.

Research Area

Cell Biology, Signal Transduction

Key Properties

• CAS Number: 402564-79-8
• MW: 909.13
• Formula: C₅₃H₆₄N₈O₆
• SMILES: C(=O)(C1=CC(=CC(C(NC(C(O)=O)C2CCCCC2)=O)=N1)C=3C=C(C(=O)N4C(CN5CCCC5)CCC4)N=C(C(NCC6=CC(=CC=C6)C7=CC=CC=C7)=O)C3)N8C(CN9CCCC9)CCC8
• Target: Others,TNF

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

58799448