R59949

SKU: orb1305277

Description

R59949 is a selective small molecule inhibitor of diacylglycerol kinase (DGK). It is a valuable research tool for investigating DGK-mediated signaling pathways in cellular and biochemical assays, aiding the study of immune cell activation, cancer biology, and neurological disorders.

Research Area

Epigenetics & Chromatin, Signal Transduction

Key Properties

• CAS Number: 120166-69-0
• MW: 489.58
• Purity: 98.82% (May vary between batches)
• Formula: C₂₈H₂₅F₂N₃OS
• SMILES: Fc1ccc(cc1)C(=C1CCN(CCn2c(=S)[nH]c3ccccc3c2=O)CC1)c1ccc(F)cc1
• Target: PKC
• Solubility: 10% DMSO+90% Corn Oil:2.5 mg/mL (5.11 mM);DMSO:60 mg/mL (122.55 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

DGK, diacylglycerol, inhibit, kinase, ligand, Inhibitor, membranes, endogenous, PKC, R 59949, R59949, R-59949, platelet, plasma, Protein kinase C

Compound Identifiers

PubChem CID

657356