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R18 TFA

SKU: orb1981675

Description

R18 TFA is a potent 14-3-3 protein-protein interaction antagonist with a K_D of 70-90 nM. It disrupts the 14-3-3/Raf-1 complex, blocking 14-3-3's protective role and promoting Raf-1 deactivation. This peptide is a valuable tool for studying 14-3-3 signaling in cancer research and cellular regulation, applicable in both in vitro and cell-based assays.

Research Area

Signal Transduction

Images & Validation

Key Properties

TargetRaf
Molecular Weight2423.73

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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R18 TFA (orb1981675)

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