R18 TFA

SKU: orb1981675

Description

R18 TFA is a potent 14-3-3 protein-protein interaction antagonist with a K_D of 70-90 nM. It disrupts the 14-3-3/Raf-1 complex, blocking 14-3-3's protective role and promoting Raf-1 deactivation. This peptide is a valuable tool for studying 14-3-3 signaling in cancer research and cellular regulation, applicable in both in vitro and cell-based assays.

Research Area

Immunology & Inflammation, Signal Transduction

Key Properties

• Target: Raf
• MW: 2423.73
• Formula: C₁₀₃H₁₅₈F₃N₂₇O₃₁S₃

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Raf