(R)-Simurosertib

SKU: orb1708734

Description

(R)-Simurosertib, also known as (R)-TAK-931, is a selective, ATP-competitive inhibitor of CDC7 kinase. This small molecule is utilized in cancer research to investigate DNA replication and cell cycle progression, with studies demonstrating its activity in both cellular and animal models of oncology.

Research Area

Cell Biology

Key Properties

• CAS Number: 1330782-69-8
• MW: 341.43
• Purity: 99.64% (May vary between batches)
• Formula: C₁₇H₁₉N₅OS
• SMILES: Cc1n[nH]cc1-c1cc2nc([nH]c(=O)c2s1)[C@H]1CC2CCN1CC2
• Target: CDK,Others
• Solubility: DMSO:67.5 mg/mL (197.7 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.86 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Simurosertib, TAK931, TAK-931, TAK 931, Cdc7, (R)-TAK-931

Compound Identifiers

PubChem CID

136443810