(R)-SCH 546738

SKU: orb2665450

Description

(R)-SCH 546738 is a potent and selective non-competitive antagonist of the human CXCR3 receptor (K_i = 0.4 nM). This orally bioavailable small molecule is a valuable research tool for investigating the role of CXCR3 in autoimmune diseases, transplant rejection, and cancer in both in vitro and in vivo models.

Research Area

Cell Biology, Immunology & Inflammation, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 2181148-54-7
• MW: 492.45
• Formula: C₂₃H₃₁Cl₂N₇O
• SMILES: ClC=1C(N2C[C@@H](CC)N(CC2)C3CCN(CC4=CC=C(Cl)C=C4)CC3)=NC(N)=C(C(N)=O)N1
• Target: CXCR

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

98005897