(R)-nitro-Blebbistatin

• Catalog Number: orb1694577
• Category: Small Molecules
• Description: (R)-nitro-Blebbistatin
• CAS Number: 1217619-62-9
• Purity: 98%
• MW: 323.3
• SMILES: O[C@@]12C(N(CC1)C3=CC=CC=C3)=NC=4C(C2=O)=CC=C(N(=O)=O)C4
• Formula: C₁₇H₁₃N₃O₄
• Biological Activity: (R)-nitro-Blebbistatin is a more stable form of (+)-blebbistatin , which is the inactive form of (-)-blebbistatin . Prolonged exposure to blue light (450-490 nm) results in degradation of blebbistatin to an inactive product via cytotoxic intermediates, which may be problematic for its use in fluorescent live cell imaging applications. The addition of a nitro group stabilizes the molecule to circumvent its degradation by prolonged blue light exposure. (R)-nitro-Blebbistatin has the same stereochemistry as the inactive (+)-blebbistatin enantiomer.
• Storage: -20°C
• Note: For research use only
• Expiration Date: 12 months from date of receipt.