R-(-)-Niguldipine hydrochloride

SKU: orb1699567

Description

R-(-)-Niguldipine hydrochloride is the less active enantiomer of niguldipine. It acts as an L-type calcium channel blocker, an alpha1A-adrenoceptor antagonist, and a potassium channel agonist by activating Ca2+-activated maxi K-channels. This multi-target profile makes it a useful research tool for studying cardiovascular physiology, hypertension, and ion channel mechanisms in vitro.

Research Area

Metabolism Research, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 113145-70-3
• MW: 646.17
• Formula: C₃₆H₄₀ClN₃O₆
• SMILES: C(CCOC(=O)C=1[C@@H](C(C(OC)=O)=C(C)NC1C)C2=CC(N(=O)=O)=CC=C2)N3CCC(CC3)(C4=CC=CC=C4)C5=CC=CC=C5.Cl
• Target: Calcium Channel,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

6918096