(R)-MLT-985

SKU: orb1687363

Description

(R)-MLT-985 is a potent and selective MALT1 protease inhibitor with an IC50 of 3 nM. It effectively blocks MALT1-dependent IL-2 production in Jurkat cells (IC50: 20 nM) and suppresses pathogenic CARD11/BCL10/MALT1 signaling and growth in ABC-DLBCL cell models, making it a valuable research tool for studying lymphomas and immune signaling pathways.

Research Area

Immunology & Inflammation

Key Properties

• CAS Number: 1832577-07-7
• MW: 448.27
• Formula: C₁₇H₁₅Cl₂N₉O₂
• SMILES: [C@@H](OC)(C)C=1N2C(N=CC1NC(NC=3C=C(Cl)C(=NC3)N4N=CC=N4)=O)=CC(Cl)=N2
• Target: Others,MALT

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

129072223