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(R)-MK-8353

SKU: orb3144650

Description

(R)-MK-8353 ((R)-SCH900353) is the R-enantiomer of MK-8353. MK-8353 (SCH900353) is a potent, selective, orally active inhibitor of ERK1 and ERK2, with IC50 values of 23.0 nM and 8.8 nM, respectively.

Research Area

Signal Transduction

Images & Validation

Key Properties

CAS Number2748457-30-7
MW691.85
FormulaC37H41N9O3S
SMILESN(C(=O)[C@]1(SC)CN(CC(=O)N2CCC(=CC2)C3=CC=C(C=C3)C4=NN(C)C=N4)CC1)C=5C=C6C(=NNC6=CC5)C=7C=CC(OC(C)C)=NC7
TargetERK

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information