(R)-MALT1-IN-3

SKU: orb1686990

Description

(R)-MALT1-IN-3 is a potent small molecule inhibitor of MALT1 protease, demonstrating an IC50 of 20 nM. It effectively suppresses IL-6 and IL-10 production in OCI-LY3 cells, making it a valuable chemical probe for researching MALT1-dependent signaling in lymphoma and autoimmune disease models.

Research Area

Immunology & Inflammation

Key Properties

• CAS Number: 2504229-61-0
• MW: 472.42
• Formula: C₂₁H₁₉F₃N₈O₂
• SMILES: [C@H](OC)(C=1C(NC(NC=2C=C(C(F)(F)F)C(=NC2)N3N=CC=N3)=O)=CN=C(C)C1C#N)C4CC4
• Target: MALT,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

155202133