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(R)-IDO/TDO-IN-1

SKU: orb2283504

Description

(R)-IDO/TDO-IN-1 is a potent dual inhibitor of indoleamine-2,3-dioxygenase (IDO) with favorable pharmacokinetics. It shows single-agent anti-tumor activity in the MC38 mouse xenograft model and demonstrates synergistic efficacy in combination with anti-PD-1 therapy, supporting its use in immuno-oncology research.

Research Area

Metabolism Research

Images & Validation

Key Properties

CAS Number2033173-00-9
MW413.49
FormulaC25H24FN5
SMILESFC1=C2[C@H](N3C(C2=CC=C1)=CN=C3)C4CCN(CC4)C5=CC=C(C=C5)C6=CN(C)N=C6
TargetIDO,Others,Indoleamine 2,3-Dioxygenase (IDO)

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

Protocol Information