(R)-Filanesib

SKU: orb1710387

Description

(R)-Filanesib is the R-enantiomer of ARRY-520 and acts as a potent, synthetic inhibitor of kinesin spindle protein (KSP) with an IC50 of 6 nM. This compound is utilized in cancer research, particularly in studies of mitosis, and has been investigated in both in vitro cellular assays and in vivo preclinical models for hematological malignancies.

Research Area

Signal Transduction

Key Properties

• CAS Number: 885060-08-2
• MW: 420.48
• Formula: C₂₀H₂₂F₂N₄O₂S
• SMILES: C(CCN)[C@]1(N(C(N(OC)C)=O)N=C(S1)C2=C(F)C=CC(F)=C2)C3=CC=CC=C3
• Target: Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

46189838