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(R)-DRF053

SKU: orb3174773

Description

(R)-DRF053 is a CDK inhibitor that suppresses Cdk5 and facilitates the formation of ductal progenitor β cells. Additionally, (R)-DRF053 inhibits the uptake of Dil-ox-LDL and the expression of the CD36 gene in U937 cells induced by advanced glycation end-products (AGEs).

Research Area

Cell Biology

Images & Validation

Key Properties

CAS Number1056016-06-8
MW417.52
FormulaC23H27N7O
SMILESN(C1=C2C(N(C(C)C)C=N2)=NC(N[C@H](CC)CO)=N1)C3=CC(=CC=C3)C4=CC=CC=N4
TargetCDK

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Protocol Information