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(R)-CDK2 degrader 6

SKU: orb3136477

Description

(R)-CDK2 degrader 6 (Compound 7) is the R enantiomer of CDK2 degrader 6. It functions as a selective molecular glue degrader for CDK2, with a DC50 of 27.0 nM within 24 hours. This compound can be utilized in breast cancer research.

Research Area

Cell Biology, Epigenetics & Chromatin, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number3083777-50-5
MW511.44
FormulaC23H22F5N5O3
SMILESC(F)(F)(F)C12CC(C1)(C2)C=3OC(N[C@@H]4[C@@H](C)N(C4)C5=CC(F)=C(C(F)=C5)[C@@H]6C(=O)NC(=O)CC6)=NN3
TargetMolecular Glues,CDK,PROTACs

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information