(R)-BAY1238097

SKU: orb1708135

Description

BAY1238097 is a potent, selective BET inhibitor that disrupts BET protein-histone binding. It exhibits anti-proliferative activity in AML and MM models in vitro and in vivo, primarily through downregulation of c-Myc and its downstream targets.

Research Area

Epigenetics & Chromatin

Key Properties

• CAS Number: 1564269-85-7
• MW: 451.56
• Purity: 98.77% (May vary between batches)
• Formula: C₂₅H₃₃N₅O₃
• SMILES: O(C)C=1C=C2C(=NN(C(NC)=O)[C@H](C)CC2=CC1OC)C3=CC=C(C=C3)N4CCN(C)CC4
• Target: Epigenetic Reader Domain
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (8.86 mM);DMSO:120 mg/mL (265.75 mM);H2O:< 0.1(insoluble)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

(R) BAY1238097, (R)BAY1238097, (R)-BAY-1238097, BAY 1238097, BAY1238097, BAY-1238097, BET

Compound Identifiers

PubChem CID

90041345