(R)-Atuveciclib

SKU: orb1710322

Description

Atuveciclib (BAY 1143572) is a potent, selective, and orally bioavailable PTEFb/CDK9 inhibitor with an IC50 of 13 nM. Its (R)-isomer shares these properties. This inhibitor is used in oncology research to study transcriptional regulation in both cellular and animal models of cancer.

Research Area

Cell Biology

Key Properties

• CAS Number: 2923012-24-0
• MW: 387.43
• Formula: C₁₈H₁₈FN₅O₂S
• SMILES: O(C)C1=C(C=CC(F)=C1)C=2N=C(NC3=CC(CS(C)(=N)=O)=CC=C3)N=CN2
• Target: CDK

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

71618220