QX-314 chloride

SKU: orb1309195

Description

QX-314 chloride

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 5369-03-9
• MW: 298.85
• Purity: 99.84%
• Formula: C₁₆H₂₇ClN₂O
• SMILES: [Cl-].CC[N+](CC)(CC)CC(=O)Nc1c(C)cccc1C
• Target: Sodium Channel
• Solubility: DMSO:1 mg/mL (3.35 mM)

Bioactivity

• In Vitro:
  QX-314 chloride (1–60 mM) directly activates TRPV1 in a concentration-dependent manner.QX-314 chloride exerts biphasic effects on transient receptor potential vanilloid subtype 1 channels (TRPV1) in vitro. QX-314 chloride (10 mM) inhibits calcium currents in hippocampal CA1 pyramidal neurons intracellular, and the low-threshold (T-type) Ca2+ currents are on average < 45% of control amplitude.

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Na+ channels, Na channels, inhibit, Inhibitor, calcium, channel, Sodium Channel, SodiumChannel, sodium channel, sodium, QX 314, QX 314 Chloride, QX 314 chloride, QX-314 Chloride, QX314 chloride, QX314 Chloride, QX314, QX-314

Compound Identifiers

PubChem CID

21462