Quizartinib HCl

SKU: orb1738080

Description

Quizartinib (AC220) is a potent and selective oral inhibitor of class III receptor tyrosine kinases, primarily targeting FLT3. It is a key research tool for studying FLT3-ITD mutant acute myeloid leukemia (AML), demonstrating efficacy in both cellular assays and in vivo models to investigate proliferation and apoptosis mechanisms.

Research Area

Cardiovascular Research, Cell Biology, Pharmacology & Drug Discovery, Signal Transduction

Key Properties

• CAS Number: 1132827-21-4
• MW: 633.59
• Formula: C₂₉H₃₄Cl₂N₆O₄S
• SMILES: O(CCN1CCOCC1)C=2C=C3C(N4C(S3)=NC(=C4)C5=CC=C(NC(NC=6C=C(C(C)(C)C)ON6)=O)C=C5)=CC2.Cl.Cl
• Target: Others,Apoptosis,FLT,Ligands for Target Protein for PROTAC

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

25184035