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Quisinostat hydrochloride

SKU: orb3174222

Description

Quisinostat (JNJ-26481585) hydrochloride is a potent and orally active pan-HDAC inhibitor (HDACi), with IC50 values ranging from 0.11 to 0.64 nM for HDAC1, HDAC2, HDAC4, HDAC10, and HDAC11. It demonstrates extensive antitumor activity and can induce autophagy (autophagy) in neuroblastoma.

Images & Validation

Key Properties

CAS Number1083078-98-1
MW430.94
FormulaC21H27ClN6O2
SMILESCl.O=C(NO)C1=CN=C(N=C1)N2CCC(CNCC3=CN(C=4C=CC=CC43)C)CC2
TargetHDAC,Autophagy

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information