Quisinostat dihydrochloride

• Catalog Number: orb1300395
• Category: Small Molecules
• Description: Quisinostat dihydrochloride
• Purity: 98.50%
• MW: 467.39
• Biological Activity: Quisinostat dihydrochloride (JNJ26854165(Quisinostat) 2HCl) is a novel second-generation HDAC inhibitor with highest potency for HDAC1 with IC50 of 0.11 nM in a cell-free assay, modest potent to HDACs 2, 4, 10, and 11; greater than 30-fold selectivity against HDACs 3, 5, 8, and 9 and lowest potency to HDACs 6 and 7. Phase 2.
• CAS Number: [875320-31-3]
• Formula: C₂₁H₂₈Cl₂N₆O₂
• SMILES: Cl.Cl.Cn1cc(CNCC2CCN(CC2)c2ncc(cn2)C(=O)NO)c2ccccc12
• Storage: -20°C
• Note: For research use only