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Quinupristin-Dalfopristin Complex (mesylate)
Catalog Number: orb1983762
| Catalog Number | orb1983762 |
|---|---|
| Category | Small Molecules |
| Description | Quinupristin-Dalfopristin Complex is a mixture of two streptogramin antibiotics. Quinupristin-dalfopristin complex is a mixture of two streptogramin antibiotics, dalfopristin, and quinupristin. Streptogramin antibiotics are divided into types A and B, which in combination can act synergistically. |
| MW | 1905.3 |
| Formula | C34H51N4O9S[CH3SO3]·C53H68N9O10S[CH3SO3] |
| SMILES | O=C6C[C@@]5([H])C(=O)N[C@@]([H])(C1=CC=CC=C1)C(=O)O[C@@](C)([H])[C@]([H])(NC(=O)C=2N=CC=CC=2O)C(=O)N[C@]([H])(CC)C(=O)N3CCC[C@@]3([H])C(=O)N(C)[C@@]([H])(C/C4=C/C=C(C=C4)N(C)C)C(=O)N5C[C@@]6([H])C[S][C@]7([H])C[N+]8CC[C@]7([H])CC8.C[S]([O-])(=O)=O.O=C2C=C[C@](C)([H])[C@]([H])(OC(=O)[C@]1([H])N(CC[C@@]1([H])[S](=O)(=O)CC[N+](CC)CC)C(=O)C3=COC(CC(=O)C[C@@](O)([H])C=C(C)C=CCN2)=N3)C(C)(C)[H].C[S]([O-])(=O)=O |
| Storage | -20°C |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |
For example, if the dosage of your experiment is 10mg/kg, the weight of each animal is 50g, and the volume of the dosing is 100μL, then the working solution concentration of your experiment is 5mg/mL. If the formula you used is 5% DMSO+ 30% PEG300+ 5% Tween 80 + 60% Saline/PBS/ddH2O, the preparation method is as follows:
Mother liquor preparation method: 5mg of drug dissolved in 100μL DMSO (mother liquor concentration is 50mg/mL). Preparation method of in vivo formulation: For 1mL of working solution preparation, take 50μL of DMSO mother liquor, add 300 μL of PEG300 to mix well and clarify, then add 50μL of Tween-80 to mix well and clarify, and finally add 600μL of Saline/PBS/ddH2O to mix well and clarify.Note:
- For Reference Only. Please choose the appropriate dissolution protocol according to your experimental animal and administration method.
- We suggest that in cell experiments, the final concentration of DMSO is not more than 0.1%, in animal experiments, for healthy mice, the final concentration of DMSO is not more than 10%; For nude or frail mice, the final concentration of DMSO is not more than 2%.
