QS-21

SKU: orb1691736

Description

QS-21 is a potent saponin adjuvant that enhances both humoral (Th2) and cellular (Th1) immunity by engaging APCs and T cells. It also activates the NLRP3 inflammasome, inducing caspase-1-dependent release of IL-1β and IL-18. This makes it a valuable tool for vaccine research in both in vivo and in vitro immunological studies.

Research Area

Immunology & Inflammation

Key Properties

• CAS Number: 141256-04-4
• MW: 1990.15
• Formula: C₉₂H₁₄₈O₄₆
• SMILES: [H][C@@](C[C@H](O)CC(=O)O[C@@]([H])(C[C@H](O)CC(=O)O[C@H]1[C@@H](C)O[C@@H](OC(=O)[C@]23CCC(C)(C)C[C@@]2([H])C2=CC[C@]4([H])[C@@]5(C)CC[C@H](O[C@]6([H])O[C@@H]([C@@H](O)[C@H](O[C@]7([H])OC[C@@H](O)[C@H](O)[C@H]7O)[C@H]6O[C@]6([H])O[C@H](CO)[C@H](O)[C@H](O)[C@H]6O)C(O)=O)[C@@](C)(C=O)[C@]5([H])CC[C@@]4(C)[C@]2(C)C[C@H]3O)[C@H](O[C@]2([H])O[C@@H](C)[C@H](O[C@]3([H])OC[C@@H](O)[C@H](O[C@]4([H])OC[C@](O)(CO)[C@H]4O)[C@H]3O)[C@@H](O)[C@H]2O)[C@H]1O)[C@@H](C)CC)(O[C@@H]1O[C@@H](CO)[C@H](O)[C@H]1O)[C@@H](C)CC
• Target: NOD-like Receptor (NLR),Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

73652135