QL-X-138 HCl

SKU: orb1962219

Description

QL-X-138 HCl is a novel selective and highly potent BTK/MNK dual-kinase inhibitor with anticancer activity that binds covalently to BTK and noncovalently to MNK. QL-X-138 HCl inhibited BTK, MNK1, and MNK2 kinases. QL-X-138 HCl has anti-dengue virus 2 activity and shows anti-proliferative activity in acute myeloid leukemia cells. QL-X-138 HCl can be used to study lymphoma and leukemia.

Research Area

Cardiovascular Research, Signal Transduction

Key Properties

• MW: 457.91
• Purity: 98.89%
• Formula: C₂₅H₂₀ClN₅O₂
• SMILES: O=C(NC1=CC(N2C(C=CC3=CN=C4C=CC(C5=CNN=C5)=CC4=C32)=O)=CC=C1C)C=C.Cl[H]
• Target: MNK,BTK

Storage & Handling

• Storage: -20°C
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

MNK,BTK