PZ15527

SKU: orb2813997

Description

PZ15527 is a proteolysis-targeting chimera (PROTAC) molecule designed to selectively degrade Bcl-xL. It serves as a chemical probe for studying Bcl-xL biology and apoptosis in cancer research, with utility demonstrated in both cellular and in vivo models.

Research Area

Pharmacology & Drug Discovery

Key Properties

• MW: 1484.13
• Formula: C₇₁H₈₂ClF₃N₁₂O₁₂S₃
• SMILES: O=C1N(C2C(NC(CC2)=O)=O)C(C(C1=CC=C3)=C3NCCOCCOCC4=CN(CCCC(N5CCN(CC[C@H](CSC6=CC=CC=C6)NC7=C(S(=O)(C(F)(F)F)=O)C=C(S(NC(C8=CC=C(N9CCN(CC%10=C(C%11=CC=C(Cl)C=C%11)CCC(C)(C)C%10)CC9)C=C8)=O)(=O)=O)C=C7)CC5)=O)N=N4)=O
• Target: PROTACs

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

132020373