PY-PAP

SKU: orb3135739

Description

PY-PAP is a photoactivatable affinity probe, derived from PY-60. It retains its cellular function of activating YAP transcription. In 293A cells, PY-PAP can label cathepsin D (CTSD) and annexin A2 (ANXA2) through UV crosslinking and click reactions. PY-PAP played a crucial role in identifying ANXA2 as a specific target of PY-60.

Research Area

Pharmacology & Drug Discovery, Stem Cell & Developmental Biology

Key Properties

• Target: YAP,Annexin A
• Molecular Weight: 462.54
• CAS Number: 2765218-57-1
• Formula: C₂₅H₃₀N₆O₃
• SMILES: O=C(NCCCN1CCN(C(=O)CCC2(N=N2)CCC#C)CC1)C3=NOC(=C3)C=4C=CC=CC4

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

YAP,Annexin A