PX20606

• Catalog Number: orb2564340
• Category: Small Molecules
• Description: PX20606 is an orally active farnesoid X receptor (FXR) agonist, demonstrating EC50 values of 220 nM (mFXR) and 50 nM (hFXR) in Gal4-FXR assays. It induces the expression of the tumor suppressor gene NDRG2 and inhibits tumor growth and metastasis in a mouse HCC model. Additionally, PX20606 exhibits hepatoprotective properties.
• Purity: 98.00%
• MW: 554.85
• CAS Number: 1268245-19-7
• Formula: C₂₉H₂₂Cl₃NO₄
• SMILES: O=C(O)C1=CC=C(C=C1)C2CC2C3=CC=C(OCC=4C(=NOC4C5CC5)C=6C(Cl)=CC=CC6Cl)C=C3Cl
• Storage: -20°C
• Note: For research use only