PW0787

SKU: orb1298085

Description

PW0787 is a potent and selective GPR52 agonist with an EC50 of 135 nM. It is orally bioavailable and capable of crossing the blood-brain barrier, making it a valuable research tool for investigating GPR52's role in CNS disorders in both in vitro and in vivo models.

Research Area

Metabolism Research, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 2624131-45-7
• MW: 460.42
• Purity: 98.52% (May vary between batches)
• Formula: C₂₃H₂₀F₄N₄O₂
• SMILES: OCCNC(=O)c1cccc2N(CCc12)c1cc(Cc2cc(F)cc(c2)C(F)(F)F)ncn1
• Target: GPCR
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.34 mM);DMSO:65 mg/mL (141.18 mM)

Bioactivity

• Target IC50:
  GPR52:135 nM(EC50)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

brain-penetrant, behavior, oral, inhibit, Inhibitor, GPR52, psychostimulant, PW 0787, PW0787, PW-0787, selective

Compound Identifiers

PubChem CID

155977949