Purinostat

SKU: orb2945819

Description

Purinostat mesylate is a selective HDACI/IIb inhibitor that suppresses Ph+ and CML-derived CD34+ leukemic cell survival by targeting key LSC factors like c-Myc and β-Catenin. It has demonstrated anti-leukemic activity in both in vitro and in vivo research models, impacting pathways such as glutamate metabolism via GLS1.

Research Area

Epigenetics & Chromatin, Molecular Biology

Key Properties

• CAS Number: 1929583-17-4
• MW: 490.518
• Formula: C₂₃H₂₆N₁₀O₃
• SMILES: O=C(NO)C1=CN=C(N=C1)N(C)CC2=NC=3C(=NC(=NC3N4CCOCC4)C=5C=CC(N)=CC5)N2C
• Target: HDAC

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

122648367