Purine riboside-5'-O-triphosphate sodium

SKU: orb2814144

Description

Purine riboside-5'-O-triphosphate sodium, a metabolite of Nebularine, serves as a biochemical tool for inhibiting DNA primase (IC50: 35 µM ATP, 28 µM GTP) and calmodulin-dependent kinase II (CaMKII; Ki: 590 µM). It is used in vitro to study nucleotide polymerization mechanisms and calcium/calmodulin-dependent signaling pathways.

Research Area

Cell Biology, Molecular Biology, Neuroscience

Key Properties

• CAS Number: 35892-95-6
• MW: 580.09
• Formula: C₁₀H₁₁N₄Na₄O₁₃P₃
• SMILES: O[C@H]1[C@@H](O[C@@H]([C@H]1O)COP(OP(OP([O-])([O-])=O)([O-])=O)([O-])=O)N2C3=NC=NC=C3N=C2.[Na+].[Na+].[Na+].[Na+]
• Target: CaMK,Nucleoside Antimetabolite/Analog,DNA/RNA Synthesis

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

90470431