Pumafentrine

SKU: orb1962249

Description

Pumafentrine (BY 343) is a dual PDE3 and PDE4 inhibitor. It has demonstrated efficacy in murine models of experimental colitis, lowering clinical disease scores and suppressing TNF expression. This small molecule is a valuable research tool for studying PDE inhibition in inflammatory bowel disease and related immunological pathways.

Research Area

Metabolism Research

Key Properties

• CAS Number: 207993-12-2
• MW: 477.64
• Purity: 99.85%
• Formula: C₂₉H₃₉N₃O₃
• SMILES: O(C)C=1C=C2C([C@]3([C@@](N=C2C4=CC=C(C(N(C(C)C)C(C)C)=O)C=C4)(CCN(C)C3)[H])[H])=CC1OCC
• Target: PDE
• Solubility: DMSO:50 mg/mL (104.68 mM)

Storage & Handling

• Storage: store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

BY 343, PDE3, PDE4

Compound Identifiers

PubChem CID

9826333