PTP1B/TC-PTP IN-1

SKU: orb2945129

Description

PTP1B/TC-PTP IN-1 is a potent dual inhibitor of the protein tyrosine phosphatases PTP1B and TC-PTP. It serves as a key ligand for constructing the PROTAC degrader DU-14, enabling the study of these targets in cellular and biochemical assays for metabolic disease and oncology research.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 3053414-48-2
• MW: 931.709
• Formula: C₄₂H₄₆BrF₂N₄O₁₁P
• SMILES: [C@@H](CC1=CC=C(C(P(=O)(O)O)(F)F)C=C1)(NC([C@H](CC2=CC=CC=C2)NC(CC3=CC(OC)=C(O)C=C3)=O)=O)C(N[C@@H](CCCCNC(=O)C4=CC(Br)=C(C)C=C4)C(O)=O)=O
• Target: Ligands for Target Protein for PROTAC

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

172263137