PTOTAC HSD17B13 degrader 1

SKU: orb2663690

Description

PTOTAC HSD17B13 Degrader 1 is a bifunctional molecule designed to degrade the protein HSD17B13, utilizing a specific ligand for the target, a linker, and an E3 ligase ligand (E3 Ligase Ligand-linker Conjugate 114). This PROTAC enables the study of HSD17B13's role in metabolic diseases like NAFLD through targeted protein degradation in biochemical and cellular research.

Research Area

Metabolism Research, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 3046195-01-8
• MW: 856.33
• Formula: C₄₅H₄₅ClF₃N₇O₅
• SMILES: O=C1N(C=2C(N1C)=CC(CCCN3CC=4C(C3)=CC=C(C4)C5=CC=6C(C=C5)=CN(N6)[C@@H]7CC[C@@H](CNC(=O)C8=C(F)C(F)=C(O)C(F)=C8)CC7)=CC2)C9C(=O)NC(=O)CC9.Cl
• Target: PROTACs

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

172420097