PTK7/β-catenin-IN-2

SKU: orb2565410

Description

PTK7/β-catenin-IN-2 (04967) is a dual inhibitor of the PTK7/β-catenin interaction and the p53-MDM2 binding, with IC50 values of 5.6 µM and 157.1 µM, respectively. It disrupts Wnt/β-catenin signaling, supporting its use in anticancer research for inhibiting Wnt-dependent cell proliferation in vitro.

Research Area

Signal Transduction, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 902434-29-1
• MW: 565.54
• Formula: C₃₀H₃₄Cl₂N₆O
• SMILES: CC=1N2C(=CC(=N2)C3=CC=C(Cl)C=C3)N=C(C)C1CCC(NCCCN4CCN(CC4)C5=CC(Cl)=CC=C5)=O
• Target: Wnt/beta-catenin

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

46255685