PTGR2-IN-1

SKU: orb1298653

Description

PTGR2-IN-1 is a potent and selective inhibitor of prostaglandin reductase 2 (PTGR2) with an IC50 of 0.7 µM. This compound enhances 15-keto-PGE2-mediated PPARγ activation in cellular assays, making it a valuable chemical probe for studying lipid metabolism and inflammation pathways in both in vitro and in vivo research contexts.

Research Area

Metabolism Research, Molecular Biology

Key Properties

• CAS Number: 349093-44-3
• MW: 310.39
• Purity: 99.13% (May vary between batches)
• Formula: C₁₉H₂₂N₂O₂
• SMILES: COc1ccccc1N1CCN(CC1)C(=O)Cc1ccccc1
• Target: PPAR,Others
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (12.89 mM);DMSO:100 mg/mL (322.18 mM)

Bioactivity

• Target IC50:
  PTGR2:0.7 μM

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

cells, inhibit, HEK293T, Inhibitor, PPARγ, PTGR2, PTGR2 IN 1, PTGR2IN1, PTGR-2-IN-1, PTGR2-IN-1, PTGR2-IN-22, transcriptional

Compound Identifiers

PubChem CID

912698