PT109

SKU: orb2695278

Description

PT109 is a multikinase inhibitor targeting JNK isoforms (IC50: 0.143-0.831 µM), SGK isoforms, and ROCK2. It exhibits anti-inflammatory and neurogenic properties and has demonstrated antiglioma activity in research by reprogramming GBM cells via the PTBP1/PKM pathway, altering their metabolic profile.

Research Area

Cell Biology, Metabolism Research, Signal Transduction, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 2059104-90-2
• MW: 429.64
• Formula: C₂₃H₃₁N₃OS₂
• SMILES: O=C(NC1CCC(NC2=CC=CC=3C=NC=CC32)CC1)CCCCC4SSCC4
• Target: JNK,SGK,ROCK

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

139297409