PSSI-51

SKU: orb3028043

Description

PSSI-51 is an orally active inhibitor of succinyl-CoA:3-ketoacid CoA transferase (SCOT) with selectivity for peripheral tissues. It effectively inhibits SCOT activity in peripheral tissues such as muscle and kidney, without affecting SCOT activity in brain tissue. By inhibiting SCOT, PSSI-51 reduces ketone body oxidation, thereby improving obesity-related hyperglycemia. It shows potential for research in type 2 diabetes (T2D) and in addressing obesity-related metabolic disorders.

Key Properties

• MW: 548.45
• Formula: C₂₈H₂₉Cl₂F₂N₃O₂
• SMILES: FC1=CC=C(C(C2=CC=C(F)C=C2)N3CCN(CCCN4C(C(C=CC=C5)=C5C4=O)=O)CC3)C=C1.Cl.Cl
• Target: Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Others