PSMA-Val-Cit-PAB-MMAE

SKU: orb1943403

Description

PSMA-Val-Cit-PAB-MMAE is a prostate-specific membrane antigen (PSMA)-directed prodrug conjugate of the cytotoxic agent monomethyl auristatin E (MMAE). It is designed for targeted chemotherapy research, enabling the study of its efficacy and mechanism in both in vitro cell assays and in vivo prostate cancer models.

Research Area

Signal Transduction

Key Properties

• CAS Number: 2748039-79-2
• MW: 2267.1
• Formula: C₁₁₄H₁₆₅ClN₂₀O₂₆
• SMILES: [C@H]([C@H](C(N[C@@H]([C@@H](O)C1=CC=CC=C1)C)=O)C)(OC)[C@]2(N(C(C[C@H]([C@@H](N(C([C@@H](NC([C@@H](N(C(OCC3=CC=C(NC([C@@H](NC([C@@H](NC(CCCC4=CN(CCCNC([C@H](CC5=CC=C(O)C=C5)NC([C@H](CC6=CC=CC=C6)NC(CCC(NCCCCCC(N(CC7=CC(Cl)=CC=C7)CCCC[C@H](NC(N[C@@H](CCC(O)=O)C(O)=O)=O)C(O)=O)=O)=O)=O)=O)=O)N=N4)=O)[C@H](C)C)=O)CCCNC(N)=O)=O)C=C3)=O)C)C(C)C)=O)[C@H](C)C)=O)C)[C@H](CC)C)OC)=O)CCC2)[H]
• Target: Drug-Linker Conjugates for ADC

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

162641039