Pseudolaric acid A-O-β-D-glucopyranoside

SKU: orb1297547

Description

Pseudolaric acid A-O-β-D-glucopyranoside

Research Area

Infectious Disease & Virology

Key Properties

• CAS Number: 98891-44-2
• MW: 550.60
• Purity: 99.70%
• Formula: C₂₈H₃₈O₁₁
• SMILES: [H][C@@]12CC[C@]3(CC=C(C)CC[C@]13OC(C)=O)C(=O)O[C@]2(C)\C=C\C=C(/C)C(=O)O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O
• Target: Antifungal
• Solubility: DMSO:25 mg/mL (45.41 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.63 mM)

Bioactivity

• In Vitro:
  A reversed phase high-performance liquid chromatography method was established for the first time to simultaneously qualify the seven major diterpenoids in Pseudolarix kaempferi, namely pseudolaric acid B O-beta-D-glucopyranoside (1), pseudolaric acid C2 (2), pseudolaric acid C1 (3), deacetylpseudolaric acid A (4), Pseudolaric acid A-O-beta-D-glucopyranoside (5), pseudolaric acid B (6) and pseudolaric acid A (7). The optimal conditions of separation and detection were achieved on an Inertsil ODS-3 column with gradient elution of methanol and 0.5% aqueous acetic acid (v/v) at the flow rate of 0.6 ml min(-1) within 40 min and detection wavelength set at 262 nm. All calibration curves showed good linear regression (r2>0.9999) within test ranges. This method provided good accuracy with recoveries in the range of 94.3-106.1% and good precision with R.S.D.s of repeatability and intermediate precision less than 0.57% and 4.67%, respectively. The method was successfully applied to qualitative and quantitative determination of 20 P. kaempferi among the 54 samples collected from different areas.

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Inhibitor, inhibit, Pseudolaric acid A O β D glucopyranoside, Pseudolaric acid A-O-b-D-glucopyranoside, Pseudolaric acid A-O-beta-D-glucopyranoside, Pseudolaric acid AOβDglucopyranoside, Pseudolaric acid A-O-β-D-glucopyranoside

Compound Identifiers

PubChem CID

44566375